Wade Wilson is a dishonorably discharged special forces operative working as a mercenary when he meets Vanessa, a prostitute. They become romantically involved, and a year later she accepts his marriage proposal. Wilson is diagnosed with terminal cancer, and leaves Vanessa without warning so she will not have to watch him die.
A mysterious recruiter approaches Wilson, offering an experimental cure for his cancer. He is taken to Ajax and Angel Dust, who inject him with a serum designed to awaken latent mutant genes. They subject Wilson to days of torture to induce stress and trigger any mutation he may have, without success. When Wilson discovers Ajax’s real name is Francis and mocks him for it, Ajax leaves Wilson in a hyperbaric chamber that periodically takes him to the verge of asphyxiation over a weekend.
This finally activates a superhuman healing ability that counteracts the cancer but leaves Wilson severely disfigured with burn-like scars over his entire body. He escapes from the chamber and attacks Ajax but relents when told that his disfigurement can be cured. Ajax subdues Wilson and leaves him for dead in the now-burning laboratory.
Wilson survives and seeks out Vanessa. He does not reveal to her he is alive fearing her reaction to his new appearance. After consulting with his best friend Weasel, Wilson decides to hunt down Ajax for the cure. He becomes a masked vigilante, adopting the name “Deadpool” (from Weasel picking him in a dead pool), and moves into the home of an elderly blind woman named Al.
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